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International Journal of Scientific and Engineering Research
ISSN Online 2229-5518
ISSN Print: 2229-5518 12    
Website: http://www.ijser.org
scirp IJSER >> Volume 2, Issue 12, December 2011
Morphophysiology Of Radiation Induced Lenticular Opacity
Full Text(PDF, 3000)  PP.  
Author(s)
Sheetal Punjani, Dr. Bharat Jethava, Dr. Preeti Shrivastava
KEYWORDS
Lenticular opacity, cataractous lens
ABSTRACT
The purpose behind the study of radiation induced lenticular opacity was to know the distribution of the lens Glucose and their interaction with environmental radiation coming from the sun. Glucose is the most important free hexose sugar in the lens. It plays an important role in energy metabolism. In the lens the biological energy is necessary for the maintenance of transparency, synthesis and repair process (Kuck, 1965). This study provides information on the potential risk of cataract development due to exposure of Non-ionizing radiation i.e. UV-radiation, Infrared radiation during their occupational activities. The entire study is carried out in two phases. Phase I the normal lenses from mice have been analyzed by the standardized method in the laboratory. The biochemical analysis was carried out. Phase II the observations obtained in the laboratory were correlated with the data of normal and different cataractous lenses of other groups. These data were outcome of the standardized methodology and exposure set up for irradiation in vivo and in vitro. Animals used for these studies were the mice (Mus musculus) and the rat (Rattus norvegiicus) of either sex. The Control animals as well as the Experiment animals were kept in laboratory condition. They were fed with standard animal food and water (Phase I-II). The experiment animals were kept in radiation chambers periodically to see the effect of radiation on their lenses. Each lens from control and experiment strains was subjected to biochemical analysis. The irradiation of the lens by the non-ionizing radiation was carried out by the in vivo and in vitro method.
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