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International Journal of Scientific and Engineering Research
ISSN Online 2229-5518
ISSN Print: 2229-5518 8    
Website: http://www.ijser.org
scirp IJSER >> Volume 2, Issue 8, August 2011
Evaluation of Analgesic and Antipyretic activity of Marsilea trifolia Blanco
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Mohammad Didar Khan
Marsilea trifolia Blanco, Marsileaceae, aqueous extract, analgesic, antipyretic, writhings, hot plates test.
The main aim of this study was to find out the Antipyretic and analgesic effects of Marsilea trifolia Blanco (Family: Marsileaceae) fresh leaf aqueous extract, a Bangladeshi medicinal plant. The extract exhibited marked analgesic effect by reduction of writhings inducted by acetic acid at dose of 100, 200 and 300mg/kg (p.o) in mice. Analgesic effect was also observed with the hot plate device maintained at 55°C. Moreover, the extract produced a significant inhibition (P<0,01) in yeast induced pyrexia in rats. This study confirms traditional use of Marsilea trifolia Blanco as remedy for fever.
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