Author Topic: The Insulin Bio Code - Standard Deviation  (Read 3245 times)

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The Insulin Bio Code - Standard Deviation
« on: January 22, 2011, 06:00:04 am »
Author : Lutvo Kurić
International Journal of Scientific & Engineering Research, Volume 1, Issue 2, November-2010
ISSN 2229-5518

The biologic role of any given protein in essential life processes, eg, insulin, depends on the positioning of its component amino acids, and is understood by the "positioning of letters forming words“. Each of these words has its biochemical base. If this base is expressed by corresponding discrete numbers, it can be seen that any given base has its own program, along with its own unique cybernetics and information characteristics.

Indeed, the sequencing of the molecule is determined not only by distin biochemical features, but also by cybernetic and information principles. For this reason, research in this field deals more with the quantitative rather than qualitative characteristcs of genetic information and its biochemical basis. For the purposes of this paper, specific physical and chemical factors have been selected in order to express the genetic information for insulin.Numerical values are them assigned to these factors, enabling them to be measured. In this way it is possible to determine oif a connection really exists between the quantitative ratios in the process of transfer of genetic information and the qualitative appearance of the insulin molecule. To  select these factors, preference is given to classical physical and chemical parameters, including the number of atoms in the relevant amino acids, their analog values, the position in these amino acids in the peptide chain, and their frenquencies.There is a arge numbers of these parameters, and each of their gives important genetic information. Going through this process, it becomes clear that there is a mathematical relationship between quantitative ratios and the qualitative appearance of the biochemical „genetic processes“ and that there is a measurement method that can be used to describe the biochemistry of insulin.

The sample of an insulin can be represented by two different forms: one is the discrete form and the other is the sequential form. In the discrete form, a insulin is represented by a set of discrete codes or a multiple dimension vector. In the sequential form, an insulin is represent by a series of amino acids according to the order of their position in the chains 1AI0. Therefore, the sequential form can naturally reflect all the information about the sequence order and lenght of an Insulin. The crux is: can we develop a different discrete form to represent an insulin that will allow accomodation of partial, if not all, sequence-order information? Since a protein sequence is usually represented by a series of amino acid codes, what kind of numerical values should be assigned to these codes in order to optimally convert the sequence-order information into a series of numbers for the discrete form representation?
How functioning of biochemistry is determined through cybernetic information principles, will be discussed further in next section.

The matrix mechanism of Insulin, the evolution of biomacromolecules and, especially, the biochemical evolution of Insulin language, have been analyzed by the application of cybernetic methods, information theory and system theory, respectively. The primary structure of a molecule of Insulin  is the exact specification of its atomic composition and the chemical bonds connecting those atoms.

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