International Journal of Scientific and Engineering Research (IJSER)

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Title: Volume 3, Issue 7, July 2012 , By IJSER Editorial Board
Post by: ijser.editor on April 12, 2014, 02:03:59 pm
IJSER July issue volume 3 issue 7 has 177 papers.
All areas of engineering and science like Computer Science, Chemistry, Physics, Biology, Medical Science, Geology,
Statistics, Accounting, Social Science, Mathematics, Management and Economics are covered (the areas are not
limited to the following):
Papers of significance in this issue.
Biomedical field paper by Dr. Ramani Iyengar, Sriranjini A.S, Jasmine on Insilico Designing and Development of
Vaccine for V.Cholerae O139 in Cholera Disease. The main aim of their project was to design and develop a vaccine
again Cholera. V.cholerae the causative agent of cholera carry strains that encode the cholera toxin. These toxins
enter Epithelial cells and after crossing host line of defense it starts colonizing itself in the small intestine. SDSC
workbench tool was utilized for screening protein sequence identical and having least E value. With Docking analysis
the epitope molecule LEALVEDL was found to be the best vaccine candidate.
The paper presented by Bhavika Desai and Pragna Parikh on Impact of Curzate (fungicide) on Hematological
Parameters of Oreochromis mossambicus focuses on environmental hazard due to recently registered fungicide
Curzate, commercially used in over 50 countries on more than 15 crops. Fresh water fish Oreochromis mossambicus
was exposed to two sub lethal concentration i.e. 4.9 mg/l and 2.45 mg/l of Curzate for a period of 21 days. The
hematological analysis showed significant reduction in RBCs count, (Hb) value, (PCV) and (MCHC), (WBCs) count,
(MCV) and (MCH) were significantly increased in the treated groups as compared the control group. The present
study shows that Curzate causes alterations in hematological parameters leading to physiological dysfunctions thus
validating the toxic effect of the fungicide on the fish
A paper of diagnostic importance for treatment of HIV through traditional medicine was presented by Venkanna
Lunavath and Estari on HIV inhibition, by Inhibition of Human Immunodeficiency Virus (HIV-1) Reverse Transcriptase
by Casia occidentalis (L) Plant Extract. They point out the fact that expensive HAART therapy is unavailable to almost
90% of the affected population. The current treatment for HIV/AIDS is called Highly Active Anti-Retroviral Therapy
(HAART) and is a combination of anti-HIV reverse transcriptase inhibitors and protease inhibitors. This reason calls
for production of less expensive and alternative AIDS therapy. The current therapy foccues on traditional medical
plants to be used as treatment for HIV. A panel of extracts of traditional medicinal plants for their activities against
HIV-1 replication was studied. The present study was aimed to evaluate the invitro anti- HIV activity of Casia
occidentalis plant extracts. Extracts were prepared from dried leaves in n-hexane, ethyl acetate and n butanol. (