Study of Microstructure and Mechanical Properties of Human Cortical Bone
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| Author(s) |
|S. Biswas, P. C. Pramanik, P. Dasgupta, A. Chanda|
| KEYWORDS |
bone porosity, fractography, hardness anisotropy, load-deformation curve, Osteon deformation.
The microstructure along with the micro-mechanical properties of bone have been extensively observed in this study. It has also been attempted to correlate the mechanical properties with the microstructural aspects. The load deformation pattern of human cortical bone (both male and female) under uniaxial compressive and tensile loading was studied. The physical properties like density and porosity of the whole femur as well as different parts of it was studied to get a mapping of the femur. Microstructure of bone, including the osteon structure, its distribution and its deformation under different stress fields have been thoroughly studied with the help of Scanning electron microscopy and reported here.
" J.Y. Rhoa, P. Ziouposb, J.D. Curreyc, G.M. Pharr. Microstructural elasticity
and regional heterogeneity in human femoral bone of various
ages examined by nano-indentation. Journal of Biomechanics 35 (2002)
 Huijie Leng, X.Neil Dong, XiaoduWang. Progressive post-yield behavior
of human cortical bone in compression for middle-aged and elderly
groups. Journal of Biomechanics 42 (2009) 491–497
 Jeffry S. Nyman, Michael Reye, Xiaodu Wang. Effect of ultrastructural
changes on the toughness of bone. Micron 36 (2005) 566–582
 R.K. Nalla a, J.J. Kruzic b, J.H. Kinney c, M. Balooch c, J.W. Ager III a,
R.O. Ritchie,a. Role of microstructure in the aging-related deterioration
of the toughness of human cortical bone. Materials Science and Engineering
C 26 (2006) 1251 – 1260
 Igor Sevostianov, Mark Kachanov. Impact of the porous microstructure
on the overall elastic properties of the osteonal cortical bone. Journal of
Biomechanics 33 (2000) 881-888
 X. Neil Dong1, X. Edward Guo. The dependence of transversely isotropic
elasticity of human femoral cortical bone on porosity. Journal of
Biomechanics 37 (2004) 1281–1287
 M. Muller, D. Mitton, P. Moilanen, V. Bousson, M. Talmant, P. Laugier.
Prediction of bone mechanical properties using QUS and pQCT: Study
of the human distal radius.
 G. Dougherty. Quantitative CT in the measurement of bone quantity
and bone quality for assessing osteoporosis. Medical Engg Physics
Vol.18 no. 7 pg 557-568. 1996.
 Philippe K. Zysset, X. Edward Guo, C. Edward Hoffler, Kristin E.
Moore, Steven A. Goldstein. Elastic modulus and hardness of cortical
and trabecular bone lamellae measured by nanoindentation in the human
femur. Journal of Biomechanics 32 (1999) 1005-1012
 S. Hengsberger, A. Kulik, and PH. Zysset. Nanoindentation Discriminates
the Elastic Properties of Individual Human Bone Lamellae Under Dry and Physiological Conditions. Bone Vol. 30, No. 1.January
 Y. N. Yeni and T. L. Norman. Fracture Toughness of Human Femoral
Neck: Effect of Microstructure, Composition, and Age. Bone Vol. 26,
No. 5 May 2000:499–504
 R.K.Nalla, J.J.Kruzic, J.H.Kinney, R.O.Ritchie. Effect of aging on the
toughness of human cortical bone: evaluation by R-curves. Bone 35
(2004) 1240 – 1246
 Kuangshin Tai1, Ming Dao1, Subra Suresh, Ahmet Palazoglu And
Christine Ortiz. Nanoscale heterogeneity promotes energy dissipation
in bone. Nature Materials VOL 6 JUNE 2007
 Peter Zioupos a, Ulrich Hansen b, John D. Currey. 2008, Microcracking
damage and the fracture process in relation to strain rate in human cortical
bone tensile failure. Journal of Biomechanics, 41, 2932–2939